Ribosomal oxygenases are structurally conserved from prokaryotes to humans.

2-Oxoglutarate (2OG)-dependent oxygenases have important roles in the regulation of gene expression via demethylation of N-methylated chromatin components and in the hydroxylation of transcription factors and splicing factor proteins. Recently, 2OG-dependent oxygenases that catalyse hydroxylation of...

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Bibliographic Details
Main Authors: Chowdhury, R, Sekirnik, R, Brissett, N, Krojer, T, Ho, C, Ng, S, Clifton, I, Ge, W, Kershaw, N, Fox, G, Muniz, JR, Vollmar, M, Phillips, C, Pilka, E, Kavanagh, K, von Delft, F, Oppermann, U, McDonough, M, Doherty, A, Schofield, C
Format: Journal article
Language:English
Published: 2014