Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
Myocardial infarction (MI), a leading cause of death around the world, displays a complex pattern of inheritance. When MI occurs early in life, genetic inheritance is a major component to risk. Previously, rare mutations in low-density lipoprotein (LDL) genes have been shown to contribute to MI risk...
المؤلفون الرئيسيون: | Do, R, Stitziel, N, Won, H, Jørgensen, AB, Duga, S, Angelica Merlini, P, Kiezun, A, Farrall, M, Goel, A, Zuk, O, Guella, I, Asselta, R, Lange, L, Peloso, G, Auer, P, Girelli, D, Martinelli, N, Farlow, D, DePristo, M, Roberts, R, Stewart, A, Saleheen, D, Danesh, J, Epstein, SE, Sivapalaratnam, S |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2014
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مواد مشابهة
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Inactivating mutations in NPC1L1 and protection from coronary heart disease.
حسب: Stitziel, N, وآخرون
منشور في: (2014) -
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
حسب: Lander, Eric Steven
منشور في: (2017) -
Systematic cell-based phenotyping of missense alleles empowers rare variant association studies: a case for LDLR and myocardial infarction.
حسب: Aenne S Thormaehlen, وآخرون
منشور في: (2015-02-01) -
Systematic Cell-Based Phenotyping of Missense Alleles Empowers Rare Variant Association Studies: A Case for LDLR and Myocardial Infarction
حسب: Thormaehlen, Aenne S., وآخرون
منشور في: (2015) -
Loss-of-function mutations in APOC3, triglycerides, and coronary disease.
حسب: Crosby, J, وآخرون
منشور في: (2014)