Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.
Myocardial infarction (MI), a leading cause of death around the world, displays a complex pattern of inheritance. When MI occurs early in life, genetic inheritance is a major component to risk. Previously, rare mutations in low-density lipoprotein (LDL) genes have been shown to contribute to MI risk...
主要な著者: | Do, R, Stitziel, N, Won, H, Jørgensen, AB, Duga, S, Angelica Merlini, P, Kiezun, A, Farrall, M, Goel, A, Zuk, O, Guella, I, Asselta, R, Lange, L, Peloso, G, Auer, P, Girelli, D, Martinelli, N, Farlow, D, DePristo, M, Roberts, R, Stewart, A, Saleheen, D, Danesh, J, Epstein, SE, Sivapalaratnam, S |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2014
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