TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism

Background Transforming growth factor-β (TGFβ) is emerging as a promising target for cancer therapy, given its ability to promote progression of advanced tumors and to suppress anti-tumor immune responses. However, TGFβ also plays multiple roles in normal tissues, particularly during organogenesis,...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Canè, S, Van Snick, J, Uyttenhove, C, Pilotte, L, Van den Eynde, BJ
Fformat: Journal article
Iaith:English
Cyhoeddwyd: BMJ Publishing Group 2021