TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism
Background Transforming growth factor-β (TGFβ) is emerging as a promising target for cancer therapy, given its ability to promote progression of advanced tumors and to suppress anti-tumor immune responses. However, TGFβ also plays multiple roles in normal tissues, particularly during organogenesis,...
Những tác giả chính: | Canè, S, Van Snick, J, Uyttenhove, C, Pilotte, L, Van den Eynde, BJ |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
BMJ Publishing Group
2021
|
Những quyển sách tương tự
-
TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism
Bằng: Stefania Canè, et al.
Được phát hành: (2021-02-01) -
Constitutive IDO1 expression in human tumors is driven by cyclooxygenase-2 and mediates intrinsic immune resistance
Bằng: Hennequart, M, et al.
Được phát hành: (2017) -
Constitutive IDO1 expression in human tumors is driven by cyclooxygenase-2 and mediates intrinsic immune resistance.
Bằng: Hennequart, M, et al.
Được phát hành: (2017) -
Isoform specific anti-TGFβ therapy enhances antitumor efficacy in mouse models of cancer
Bằng: Aditi Gupta, et al.
Được phát hành: (2021-11-01) -
TGF-β Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions.
Bằng: Xiaofeng Chen, et al.
Được phát hành: (2016-01-01)