Melatonin phase advances circadian rhythm.

We studied the effect of acute (1 day) and subacute (7 days) treatment with melatonin (0.5 mg) on the endogenous rhythms of melatonin secretion in 12 healthy male volunteers, using a placebo-controlled, double-blind, cross-over design. Melatonin given at 1700 h for 7 days significantly advanced the...

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Bibliographic Details
Main Authors: Attenburrow, M, Dowling, B, Sargent, P, Sharpley, A, Cowen, P
Format: Journal article
Language:English
Published: 1995