Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2α gain-of-function mutation.

Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2α gain-of-function mutation.

The hypoxia-inducible factors (HIFs; isoforms HIF-1α, HIF-2α, HIF-3α) mediate many responses to hypoxia. Their regulation is principally by oxygen-dependent degradation, which is initiated by hydroxylation of specific proline residues followed by binding of von Hippel-Lindau (VHL) protein. Chuvash p...

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Detaylı Bibliyografya
Asıl Yazarlar: Formenti, F, Beer, P, Croft, Q, Dorrington, K, Gale, D, Lappin, T, Lucas, G, Maher, E, Maxwell, P, McMullin, M, O'Connor, D, Percy, M, Pugh, C, Ratcliffe, P, Smith, T, Talbot, N, Robbins, P
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2011

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