In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance.

The advent of hyperpolarized (13)C magnetic resonance (MR) has provided new potential for the real-time visualization of in vivo metabolic processes. The aim of this work was to use hyperpolarized [1-(13)C]pyruvate as a metabolic tracer to assess noninvasively the flux through the mitochondrial enzy...

Повний опис

Бібліографічні деталі
Автори: Schroeder, M, Cochlin, L, Heather, L, Clarke, K, Radda, G, Tyler, D
Формат: Journal article
Мова:English
Опубліковано: 2008