In vivo imaging reveals novel aspects of retinal disease progression in Rs1h(-/Y) mice but no therapeutic effect of carbonic anhydrase inhibition.

PURPOSE: X-linked juvenile retinoschisis (XLRS) is the most common juvenile maculopathy in men and is caused by mutations in the gene encoding retinoschisin (RS1). Evidence in the literature on the therapeutic effect of carboanhydrase inhibitors (CAIs) to treat schisis formation in the retina has r...

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Bibliographic Details
Main Authors: Zhour, A, Bolz, S, Grimm, C, Willmann, G, Schatz, A, Weber, B, Zrenner, E, Fischer, M
Format: Journal article
Language:English
Published: 2012