CRAC channels drive digital activation and provide analog control and synergy to Ca 2+-dependent gene regulation

Ca 2+-dependent gene expression is critical for cell growth, proliferation, plasticity, and adaptation [1-3]. Because a common mechanism in vertebrates linking cytoplasmic Ca 2+ signals with activation of protein synthesis involves the nuclear factor of activated T cells (NFAT) family of transcripti...

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Bibliographic Details
Main Authors: Kar, P, Nelson, C, Parekh, AB
Format: Journal article
Language:English
Published: 2012