Activation-induced killer cell immunoglobulin-like receptor 3DL2 binding to HLA-B27 licenses pathogenic T cell differentiation in spondyloarthritis

In the spondyloarthritides (SpA), increased numbers of CD4+ T cells express killer cell immunoglobulin-like receptor 3DL2 (KIR-3DL2). The aim of this study was to determine the factors that induce KIR-3DL2 expression, and to characterize the relationship between HLA-B27 and the phenotype and functio...

Full description

Bibliographic Details
Main Authors: Ridley, A, Hatano, H, Wong-Baeza, I, Shaw, J, Matthews, K, Al-Mossawi, H, Ladell, K, Price, D, Bowness, P, Kollnberger, S
Format: Journal article
Language:English
Published: Wiley 2016