Integrating chromatin and development: LDB1 regulates genome architecture and gene expression in motor neuron differentiation

<p>Dynamic changes in chromatin architecture underpin gene expression in development. The chromatin integrator protein LDB1 is a key regulatory node in the organization of developmentally-specific gene expression programs, particularly in motor neurons (MNs) of the vertebrate spinal cord. By c...

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Bibliographic Details
Main Author: Demmerle, J
Other Authors: Macfarlan, T
Format: Thesis
Language:English
Published: 2019
Subjects: