Selective protein degradation by ligand-targeted enzymes: towards the creation of catalytic antagonists.
Molecular angler fish: By precisely positioning different binding ligands (L) around the active site "mouth" of a degradative proteinase enzyme, target proteins (TP) can be plucked from solution, locked in position adjacent to the catalytic triad "jaws", and in this way readily a...
| Egile Nagusiak: | , , , , , , , , |
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| Formatua: | Journal article |
| Hizkuntza: | English |
| Argitaratua: |
2003
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