Direct imaging of the recruitment and phosphorylation of S6K1 in the mTORC1 pathway in living cells

Knowledge of protein signalling pathways in the working cell is seen as a primary route to identifying and developing targeted medicines. In recent years there has been a growing awareness of the importance of the mTOR pathway, making it an attractive target for therapeutic intervention in several d...

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Bibliographic Details
Main Authors: Ahmed, A, Owens, R, Stubbs, C, Parker, A, Hitchman, R, Yadav, R, Dumoux, M, Hawes, C, Botchway, S
Format: Journal article
Language:English
Published: Nature Research 2019