Single-molecule investigation of directional transport through a bacterial transmembrane pore

Colicin E9 (ColE9) crosses the outer membrane of E. coli by passing through the trimeric OmpF porin. Entry is initiated by an intrinsically unstructured N-terminal domain (IUTD), which has two OmpF-binding sites (OBS). The IUTD threads through a first subunit of OmpF, reverses direction and enters a...

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Bibliographic Details
Main Authors: Lee, S, Ionescu, S, Housden, N, Kleanthous, C, Bayley, J
Format: Conference item
Published: Springer 2017