High-frequency stimulation of the subthalamic nucleus suppresses oscillatory beta activity in patients with Parkinson's disease in parallel with improvement in motor performance.

High-frequency stimulation (HFS) of the subthalamic nucleus (STN) is a well-established therapy for patients with severe Parkinson's disease (PD), but its mechanism of action is unclear. Exaggerated oscillatory synchronization in the beta (13-30 Hz) frequency band has been associated with brady...

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Bibliographic Details
Main Authors: Kühn, A, Kempf, F, Brücke, C, Gaynor Doyle, L, Martinez-Torres, I, Pogosyan, A, Trottenberg, T, Kupsch, A, Schneider, G, Hariz, M, Vandenberghe, W, Nuttin, B, Brown, P
Format: Journal article
Language:English
Published: 2008