Nonimmune IgM, but not IgG binds to the surface of Plasmodium falciparum-infected erythrocytes and correlates with rosetting and severe malaria.

Recent work suggests that IgG and IgM from nonimmune human serum (natural antibodies) bind to the surface of Plasmodium falciparum-infected erythrocytes and contribute to rosette formation by stabilizing the interaction between infected and uninfected erythrocytes. Here we show, in both laboratory c...

Full description

Bibliographic Details
Main Authors: Rowe, J, Shafi, J, Kai, O, Marsh, K, Raza, A
Format: Journal article
Language:English
Published: 2002