Nonimmune IgM, but not IgG binds to the surface of Plasmodium falciparum-infected erythrocytes and correlates with rosetting and severe malaria.

Recent work suggests that IgG and IgM from nonimmune human serum (natural antibodies) bind to the surface of Plasmodium falciparum-infected erythrocytes and contribute to rosette formation by stabilizing the interaction between infected and uninfected erythrocytes. Here we show, in both laboratory c...

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Những tác giả chính: Rowe, J, Shafi, J, Kai, O, Marsh, K, Raza, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2002