Quantifying individual noxious-evoked baseline sensitivity to optimise analgesic trials in neonates

Despite the high burden of pain experienced by hospitalised neonates, there are few analgesics with proven efficacy. Testing analgesics in neonates is experimentally and ethically challenging and minimising the number of neonates required to demonstrate efficacy is essential. EEG (electroencephalogr...

Full description

Bibliographic Details
Main Authors: Cobo, MM, Hartley, C, Gursul, D, Andritsou, F, van der Vaart, M, Schmidt Mellado, G, Baxter, L, Duff, EP, Buckle, M, Evans Fry, R, Green, G, Hoskin, A, Rogers, R, Adams, E, Moultrie, F, Slater, R
Format: Journal article
Language:English
Published: eLife Sciences Publications 2021