Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition.

T cell antigen recognition is accompanied by cytoskeletal polarization towards the APC and large-scale redistribution of cell surface molecules into 'supramolecular activation clusters' (SMACs), forming an organized contact interface termed the 'immunological synapse' (IS). Molec...

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Bibliographic Details
Main Authors: Anton van der Merwe, P, Davis, S, Shaw, A, Dustin, M
Format: Journal article
Language:English
Published: 2000