Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1.

CD4 is the primary receptor for human immunodeficiency virus (HIV). The binding site for the surface glycoprotein of HIV type 1 (HIV-1), gp120, has been mapped to the C'-C" region of domain 1 of CD4. Previously, we have shown that a mutant of rat CD4, in which this region was exchanged for...

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Bibliographic Details
Main Authors: Simon, J, Stumbles, P, Signoret, N, Somoza, C, Puklavec, M, Sattentau, Q, Barclay, A, James, W
Format: Journal article
Language:English
Published: 1997