Mechanisms and structures of crotonase superfamily enzymes--how nature controls enolate and oxyanion reactivity.

Structural and mechanistic studies on the crotonase superfamily (CS) are reviewed with the aim of illustrating how a conserved structural platform can enable catalysis of a very wide range of reactions. Many CS reactions have precedent in the 'carbonyl' chemistry of organic synthesis; they...

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Bibliographic Details
Main Authors: Hamed, R, Batchelar, E, Clifton, I, Schofield, C
Format: Journal article
Language:English
Published: 2008