Mechanisms and structures of crotonase superfamily enzymes--how nature controls enolate and oxyanion reactivity.
Structural and mechanistic studies on the crotonase superfamily (CS) are reviewed with the aim of illustrating how a conserved structural platform can enable catalysis of a very wide range of reactions. Many CS reactions have precedent in the 'carbonyl' chemistry of organic synthesis; they...
Main Authors: | Hamed, R, Batchelar, E, Clifton, I, Schofield, C |
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Format: | Journal article |
Language: | English |
Published: |
2008
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