Metabolomic profiling in acute ST‐segment–elevation myocardial infarction identifies succinate as an early marker of human ischemia–reperfusion injury
<strong>Background</strong> Ischemia–reperfusion injury following ST‐segment–elevation myocardial infarction (STEMI) is a leading determinant of clinical outcome. In experimental models of myocardial ischemia, succinate accumulation leading to mitochondrial dysfunction is a major cause o...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Heart Association
2018
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