Crystal structure of the secretory isozyme of mammalian carbonic anhydrases CA VI: implications for biological assembly and inhibitor development.

Zn(2+)-dependent carbonic anhydrases (CA) catalyse the reversible hydration of carbon dioxide to bicarbonate and participate in diverse physiological processes, hence having manifold therapeutic potentials. Among the 15 human CAs with wide-ranging sub-cellular localisation and kinetic properties, CA...

詳細記述

書誌詳細
主要な著者: Pilka, E, Kochan, G, Oppermann, U, Yue, W
フォーマット: Journal article
言語:English
出版事項: 2012