Cluster effect for SNP–SNP interaction pairs for predicting complex traits

Single nucleotide polymorphism (SNP) interactions are the key to improving polygenic risk scores. Previous studies reported several significant SNP–SNP interaction pairs that shared a common SNP to form a cluster, but some identified pairs might be false positives. This study aims to identify factor...

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Détails bibliographiques
Auteurs principaux:	Lin, H, Mazumder, H, Sarkar, I, Huang, P, Eeles, RA, Kote-Jarai, Z, Muir, KR, Schleutker, J, Pashayan, N, Batra, J, Neal, DE, Nielsen, SF, Nordestgaard, BG, Grönberg, H, Wiklund, F, MacInnis, RJ, Haiman, CA, Travis, RC, Stanford, JL, Kibel, AS, Cybulski, C, Khaw, K, Maier, C, Thibodeau, SN
Format:	Journal article
Langue:	English
Publié:	Nature Research 2024

Cluster effect for SNP–SNP interaction pairs for predicting complex traits

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