Cluster effect for SNP–SNP interaction pairs for predicting complex traits

Cluster effect for SNP–SNP interaction pairs for predicting complex traits

Single nucleotide polymorphism (SNP) interactions are the key to improving polygenic risk scores. Previous studies reported several significant SNP–SNP interaction pairs that shared a common SNP to form a cluster, but some identified pairs might be false positives. This study aims to identify factor...

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Bibliographic Details
Main Authors: Lin, H, Mazumder, H, Sarkar, I, Huang, P, Eeles, RA, Kote-Jarai, Z, Muir, KR, Schleutker, J, Pashayan, N, Batra, J, Neal, DE, Nielsen, SF, Nordestgaard, BG, Grönberg, H, Wiklund, F, MacInnis, RJ, Haiman, CA, Travis, RC, Stanford, JL, Kibel, AS, Cybulski, C, Khaw, K, Maier, C, Thibodeau, SN
Format: Journal article
Language:English
Published: Nature Research 2024

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