The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4
Macrophages constitute an important reservoir of HIV-1 infection, yet HIV-1 entry into these cells is poorly understood due to the difficulty in genetically manipulating primary macrophages. We developed an effective genetic approach to manipulate the sub-cellular distribution of CD4 in macrophages,...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Public Library of Science
2014
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