Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth.

Genome sequences predict the presence of many 2-oxoglutarate (2OG)-dependent oxygenases of unknown biochemical and biological functions in Drosophila. Ribosomal protein hydroxylation is emerging as an important 2OG oxygenase catalyzed pathway, but its biological functions are unclear. We report inve...

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Hlavní autoři: Katz, M, Acevedo, J, Loenarz, C, Galagovsky, D, Liu-Yi, P, Pérez-Pepe, M, Thalhammer, A, Sekirnik, R, Ge, W, Melani, M, Thomas, MG, Simonetta, S, Boccaccio, G, Schofield, C, Cockman, M, Ratcliffe, P, Wappner, P
Médium: Journal article
Jazyk:English
Vydáno: National Academy of Sciences 2014