Viral antagonism of extracellular cGAMP responses
<p>The presence of viral DNA outside of the nucleus is detected by the pattern recognition receptor cGAS during infection. cGAS then generates the cyclic dinucleotide 2’3’-cGAMP, which activates the central hub of DNA sensing – STING. This results in the production of proinflammatory cytokines...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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