Viral antagonism of extracellular cGAMP responses

<p>The presence of viral DNA outside of the nucleus is detected by the pattern recognition receptor cGAS during infection. cGAS then generates the cyclic dinucleotide 2’3’-cGAMP, which activates the central hub of DNA sensing – STING. This results in the production of proinflammatory cytokines...

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Bibliografski detalji
Glavni autor: Blest, HTW
Daljnji autori: Rehwinkel, J
Format: Disertacija
Jezik:English
Izdano: 2022
Teme: