Optimization in osmolality and range of density of a continuous ficoll-sodium-diatrizoate gradient for isopycnic purification of isolated human islets.

INTRODUCTION: According to previous estimates from large animals and man, a minimum of approximately 5000 to 6000 engrafted islet equivalents (IEQ)/kg recipient weight is critical to establish insulin independence. Utilizing a single donor, this threshold yield of purified islets can be retrieved fr...

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Manylion Llyfryddiaeth
Prif Awduron: Eckhard, M, Brandhorst, D, Brandhorst, H, Brendel, MD, Bretzel, R
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2004