Mechanisms of induction and modulation of the pro-inflammatory cytokine interleukin-1beta

<p>Interleukin (IL)-1beta is a powerful pro-inflammatory cytokine with important roles in directing both innate and adaptive immunity. As a result, its production is tightly controlled, with the synthesis of an inactive form (pro-IL-1beta) and the requirement of a second signal. This induces...

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Bibliographic Details
Main Author: Yip, RHN
Other Authors: Cerundolo, V
Format: Thesis
Language:English
Published: 2012
Subjects: