JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues.

JMY is a p300-binding protein with dual action: by enhancing P53 transcription in the nucleus, it plays an important role in the cellular response to DNA damage, while by promoting actin filament assembly in the cytoplasm; it induces cell motility in vitro. Therefore, it has been argued that, depend...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Adighibe, O, Turley, H, Leek, R, Harris, A, Coutts, A, La Thangue, N, Gatter, K, Pezzella, F
التنسيق: Journal article
اللغة:English
منشور في: Springer Verlag 2014