Systems-level analysis of monocyte responses in inflammatory bowel disease identifies IL-10 and IL-1 cytokine networks that regulate IL-23

Dysregulated intestinal immune responses are the cause of inflammatory bowel diseases (IBD). Using single-cell and bulk transcriptomic approaches we investigate the responses of monocytes and peripheral blood mononuclear cells to multiple stimuli and relate those to transcriptional responses in the...

Full description

Bibliographic Details
Main Authors:	Aschenbrenner, D, Quaranta, M, Banerjee, S, Ilott, N, Jansen, J, Steere, B, Chen, Y, Ho, S, Cox, K, Arancibia, C, Coles, M, Gaffney, E, Travis, S, Denson, L, Kugathasan, S, Schmitz, J, Powrie, F, Sansom, S, Uhlig, H
Format:	Journal article
Published:	2019

Systems-level analysis of monocyte responses in inflammatory bowel disease identifies IL-10 and IL-1 cytokine networks that regulate IL-23

Similar Items