Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

Min mice provide a good model of human familial adenomatous polyposis. Recently, we have reported on two recombinant inbred lines (I and V) and the location of a modifier (Mom3) close to Apc, which altered polyp numbers in our mice possibly by modifying the frequency of wild-type (WT) allele loss at...

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Bibliographic Details
Main Authors: Suraweera, N, Haines, J, McCart, A, Rogers, P, Latchford, A, Coster, M, Polanco-Echeverry, G, Guenther, T, Wang, J, Sieber, O, Tomlinson, I, Silver, A
Format: Journal article
Language:English
Published: 2006