A primary hydrogen-deuterium isotope effect observed at the single-molecule level.

The covalent chemistry of reactants tethered within a single protein pore can be monitored by observing the time-dependence of ionic current flow through the pore, which responds to bond making and breaking in individual reactant molecules. Here we use this 'nanoreactor' approach to examin...

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Bibliographic Details
Main Authors: Lu, S, Li, W, Rotem, D, Mikhailova, E, Bayley, H
Format: Journal article
Language:English
Published: 2010