New developments of alignment-free sequence comparison: measures, statistics and next-generation sequencing.

With the development of next-generation sequencing (NGS) technologies, a large amount of short read data has been generated. Assembly of these short reads can be challenging for genomes and metagenomes without template sequences, making alignment-based genome sequence comparison difficult. In additi...

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Bibliographic Details
Main Authors: Song, K, Ren, J, Reinert, G, Deng, M, Waterman, MS, Sun, F
Format: Journal article
Language:English
Published: Oxford University Press 2014