ACME dissociation: a versatile cell fixation-dissociation method for single-cell transcriptomics

<p>Single-cell sequencing technologies are revolutionizing biology, but they are limited by the need to dissociate live samples. Here, we present ACME (ACetic-MEthanol), a dissociation approach for single-cell transcriptomics that simultaneously fixes cells. ACME-dissociated cells have high RN...

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Bibliographic Details
Main Authors: García-Castro, H, Kenny, NJ, Iglesias, M, Álvarez-Campos, P, Mason, V, Elek, A, Schönauer, A, Sleight, VA, Neiro, J, Aboobaker, A, Permanyer, J, Irimia, M, Sebé-Pedrós, A, Solana, J
Format: Journal article
Language:English
Published: BioMed Central 2021