Structure of a cephalosporin synthase.

Penicillins and cephalosporins are among the most widely used therapeutic agents. These antibiotics are produced from fermentation-derived materials as their chemical synthesis is not commercially viable. Unconventional steps in their biosynthesis are catalysed by Fe(II)-dependent oxidases/oxygenase...

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Bibliographic Details
Main Authors: Valegård, K, van Scheltinga, A, Lloyd, MD, Hara, T, Ramaswamy, S, Perrakis, A, Thompson, A, Lee, H, Baldwin, J, Schofield, C, Hajdu, J, Andersson, I
Format: Journal article
Language:English
Published: 1998