Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivo.

Understanding the role of cytotoxic T lymphocytes (CTLs) in controlling HIV-1 infection is vital for vaccine design. However, it is difficult to assess the importance of CTLs in natural infection. Different human leukocyte antigen (HLA) class I alleles are associated with different rates of progress...

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Bibliographic Details
Main Authors: Asquith, B, Edwards, C, Lipsitch, M, Mclean, A
Format: Journal article
Language:English
Published: 2006