Monovalent, reduced-size quantum dots for imaging receptors on living cells.

We describe a method to generate monovalent quantum dots (QDs) using agarose gel electrophoresis. We passivated QDs with a carboxy-terminated polyethylene-glycol ligand, yielding particles with half the diameter of commercial QDs, which we conjugated to a single copy of a high-affinity targeting moi...

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Bibliographic Details
Main Authors: Howarth, M, Liu, W, Puthenveetil, S, Zheng, Y, Marshall, L, Schmidt, M, Wittrup, K, Bawendi, MG, Ting, A
Format: Journal article
Language:English
Published: 2008