Anti-IL-17A treatment reduces clinical score and VCAM-1 expression detected by in vivo magnetic resonance imaging in chronic relapsing EAE ABH mice.

IL-17 is argued to play an important role in the multiple sclerosis-like disease experimental autoimmune encephalitis (EAE). We investigated the therapeutic effects of anti-IL-17A in a chronic relapsing EAE ABH mouse model using conventional scoring, quantitative behavioral outcomes, and a novel vas...

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Main Authors: Mardiguian, S, Serres, S, Ladds, E, Campbell, S, Wilainam, P, McFadyen, C, McAteer, M, Choudhury, R, Smith, P, Saunders, F, Watt, G, Sibson, N, Anthony, D
Format: Journal article
Language:English
Published: 2013