Elucidating the mechanism of action of novel small molecule activators of differentiation in acute myeloid leukemic cells
<p>Acute Myeloid Leukaemia (AML) is a haematopoietic malignancy which comprises of different genetic subtypes with a common hallmark of differentiation arrest. In abnormal haematopoiesis, overcoming the differentiation blockade has emerged as an attractive therapeutic strategy. While current a...
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Format: | Thesis |
Language: | English |
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2020
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