Elucidating the mechanism of action of novel small molecule activators of differentiation in acute myeloid leukemic cells

<p>Acute Myeloid Leukaemia (AML) is a haematopoietic malignancy which comprises of different genetic subtypes with a common hallmark of differentiation arrest. In abnormal haematopoiesis, overcoming the differentiation blockade has emerged as an attractive therapeutic strategy. While current a...

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Bibliographic Details
Main Author: Kumar, P
Other Authors: Russell, A
Format: Thesis
Language:English
Published: 2020
Subjects: