Reduced neural response to reward following 7 days treatment with the cannabinoid CB1 antagonist rimonabant in healthy volunteers.

Reduced subjective experience of reward (anhedonia) is a key symptom of major depression. The anti-obesity drug and cannabinoid type 1 receptor (CB(1)) antagonist, rimonabant, is associated with significant rates of depression and anxiety in clinical use and was recently withdrawn from the market be...

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Bibliographic Details
Main Authors: Horder, J, Harmer, C, Cowen, P, Mccabe, C
Format: Journal article
Language:English
Published: 2010