Disentangling the relationship between Lewy bodies and nigral neuronal loss in Parkinson's disease

Progressive rostral spread of Lewy body (LB) pathology is thought to reflect the clinical course of Parkinson's disease (PD) although several studies have suggested that LBs are not the toxic species responsible for cell death. We investigated the relationship between nigral dopaminergic cell l...

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Bibliographic Details
Main Authors: O'Sullivan, S, Collins, C, Petrie, A, Holton, J, Revesz, T, Lees, A, Parkkinen, L
Format: Journal article
Published: IOS Press 2011