Faster adaptation in smaller populations: Counterintuitive evolution of HIV during childhood infection.

Analysis of HIV-1 gene sequences sampled longitudinally from infected individuals can reveal the evolutionary dynamics that underlie associations between disease outcome and viral genetic diversity and divergence. Here we extend a statistical framework to estimate rates of viral molecular adaptation...

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Bibliographic Details
Main Authors: Raghwani, J, Bhatt, S, Pybus, O
Format: Journal article
Language:English
Published: Public Library of Science 2016