Faster adaptation in smaller populations: Counterintuitive evolution of HIV during childhood infection.
Analysis of HIV-1 gene sequences sampled longitudinally from infected individuals can reveal the evolutionary dynamics that underlie associations between disease outcome and viral genetic diversity and divergence. Here we extend a statistical framework to estimate rates of viral molecular adaptation...
Main Authors: | Raghwani, J, Bhatt, S, Pybus, O |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2016
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