Structural basis of fumarate hydratase deficiency.

Fumarate hydratase catalyzes the stereospecific hydration across the olefinic double bond in fumarate leading to L-malate. The enzyme is expressed in mitochondrial and cytosolic compartments, and participates in the Krebs cycle in mitochondria, as well as in regulation of cytosolic fumarate levels....

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Váldodahkkit: Picaud, S, Kavanagh, K, Yue, W, Lee, W, Muller-Knapp, S, Gileadi, O, Sacchettini, J, Oppermann, U
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: Springer Netherlands 2011