Development of a rapid, small-scale DNA repair assay for use on clinical samples.
Double-strand breaks (DSBs) are the most lethal form of DNA damage. They can be repaired by one of two pathways, homologous recombination and non-homologous end joining (NHEJ). A NHEJ assay has previously been reported which measures joining using cell-free extracts and a linearised plasmid as DNA s...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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